Sigma

1-Nitrosopiperidine

N6007

DOWNLOAD MSDS (PDF)

  • CAS Number: 100-75-4

  • Empirical Formula (Hill Notation): C5H10N2O

  • Molecular Weight: 114.15

  • EC Number: 202-886-6

  • MDL number: MFCD00023652

  • PubChem Substance ID: 24897764

1-Nitrosopiperidine
#

Properties

Related CategoriesCancer Research, Carcinogens
density1.06 g/mL(lit.)
storage temp.2-8°C

Description

Biochem/physiol Actions

Carcinogen that induces benign and malignant tumors of the respiratory tract, stomach and esophagus in rodents; potent nasal carcinogen in rats.

Price and Availability

Customers Also Purchased

1582401-Nitrosopyrrolidine

99%

442685N-Nitrosodi-n-butylamine

analytical standard

48554N-Nitrosodi-n-propylamine

analytical standard, ampule of 100 mg

48552N-Nitrosodimethylamine

analytical standard

N7382Nitrosomorpholine


Documents

  • Bulk Quote-Order Product
  • MSDS (PDF)

Certificate of Analysis

Certificate of Origin

Structure Search
Similar Products

Safety Information

SymbolGHS06GHS08  GHS06, GHS08
Signal wordDanger
Hazard statementsH301-H351
Precautionary statementsP281-P301 + P310
Personal Protective EquipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard CodesT
Risk Statements25-40
Safety Statements53-23-26-36/37/39-45
RIDADRUN 2810 6.1/PG 3
WGK Germany3
RTECSTN2100000
Technical information & documentation associated with this product is available in the Safety & Documentation tab.

Articles

Carcinogenesis and Epigenetics

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete. The expansion of the carcinogenesi...
Vicki Caligur
BioFiles 2008, 3.5, 18.
Keywords: Acetylations, Adhesion, Alkylations, Apoptosis, Cancer, Carcinogens, Cell division, Cell proliferation, Cell signaling, DNA microarrays, Drug discovery, Environmental, Epigenetics, Gene expression, Genetic, Hormones, Metabolism, Methylations, Microarray Analysis, Mutagens, PAGE, Recombination, Reductions, Transcription, transformation

DNA Damage and Repair

Damage to cellular DNA is involved in mutagenesis and the development of cancer. The DNA in a human cell undergoes several thousand to a million damaging events per day, generated by both external (e...
BioFiles 2007, 2.4, 20.
Keywords: AGE, Alkylations, Apoptosis, Biochemistry, Cancer, Carcinogens, Catalysis, Clinical, DNA replication, Deaminations, Environmental, Gene expression, Metabolites, Methylations, Mutagens, Oxidations, PAGE, Polymorphisms, Rearrangements, Recombination, Substitutions, Transcription

References

Wong, H.L., et al., Preferential metabolic activation of N-nitrosopiperidine as compared to its structural homologue N-nitrosopyrrolidine by rat nasal mucosal microsomes. Chem. Res. Toxicol. 16, 1298-1305, (2003)

Wong, H.L., et al., Comparative metabolism of N-nitrosopiperidine and N-nitrosopyrrolidine by rat liver and esophageal microsomes and cytochrome P450 2A3. Carcinogenesis 24, 291-300, (2003)


Share your experience with this product and how it worked in your specific application. We value your opinion and your colleagues will too!

Learn more at www.sigmaaldrich.com/reviews.

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?